Hyphens, En Dashes, Em Dashes

Q. I’ve tried to Look It Up, and I know other people are curious about this question, too—some of ’em can’t even sleep at night for worrying about it—so I’m writing you, O Mighty Editors, to ask where do the hyphens go in the phrase “two and a half times the price”???

A. They go away into some other phrase.

[This answer relies on the 17th edition of CMOS (2017) unless otherwise noted.]