Q. Can you please add “wise” to the hyphenation table? I’m curious if you would use a hyphen in a sentence like “Accessibility-wise, my favorite city was Tokyo.”
A. Hyphenation-wise, the adverb combining form -wise would be treated like the adjective combining form -like. And according to the entry for “like” in the hyphenation table at CMOS 7.89 (section 3), compounds formed with that term are closed if they’re listed as such in Merriam-Webster; otherwise, they’re hyphenated in any position in a sentence. Likewise for -wise.
So accessibility-wise (and, as we’ve just seen, hyphenation-wise) would be written with a hyphen (because those terms aren’t in Merriam-Webster), whereas clockwise (and counterclockwise), crabwise, and (more déjà vu) likewise and otherwise—all in Merriam-Webster—would be closed.
Another term that works this way is -wide (the last entry in section 3 of the hyphenation table), as in worldwide (in the dictionary) but university-wide (not in the dictionary). We’ll consider adding -wise to a future edition of CMOS; until then, we’d advise you to proceed analogy-wise.