Hyphens, En Dashes, Em Dashes
Q. I’m interested in how you would treat the following issue of double punctuation: U.S.-oriented. I decided to omit the hyphen, which I would have otherwise used, because I didn’t like the way it looked following an abbreviation period.
A. It may look a little odd, but the hyphen is conventional there, because omitting it could cause readers to mistake “oriented” for a verb. If your publication’s style permits, you can follow CMOS 16 in omitting the periods: US-oriented.